To keep warm during the cold winter months, the deer mice huddle together in groups to keep warm and reduce the temperatures of their bodies by undergoing daily torpor.
In prairie habitats they will build their nests just below the surface.
They are nocturnal.
They are omnivores and eat plants, seeds (important for seed dispersing), flowers, fruits, nuts, and insects.
They get their name from the color pattern of its coat, which closely resembles that of the white-tailed deer.
Whiskers allow mice to feel temperature changes as well as the surface when moving around.